fluconazole

The story of the discovery of fluconazole is presented, together with detailed accounts of in vitro testing of susceptibilty, and the dru's pharmacokinetics, pharmacodynamics, safety profile, effects on mammalian cytochrome P450-mediated reactions, and uses in a wide variety of clinical contexts. this is a major reference source on fluconazole for all those involved in the management of patients with fungal infections.